Design, synthesis and biological evaluation of novel chromone-maleimide hybrids as potent anti-inflammatory agents against LPS-induced acute lung injury
Yali Zhang, Zhengwei Xu, Lingling Zhan, Yi Gao, Bin Zheng, Yan Zhou, Yaoguang Sheng, Guang Liang, Zengqiang Song
Topics & Concepts
ChromoneMaleimideChemistryLipopolysaccharideIn vivoPharmacologyAnti-inflammatoryInflammationPotencyIn vitroTumor necrosis factor alphaBiochemistryImmunologyStereochemistryMedicineBiologyOrganic chemistryBiotechnologySynthesis of Organic CompoundsBioactive natural compoundsBiological Activity of Diterpenoids and Biflavonoids