Metastatic and sentinel lymph node mapping using intravenously delivered Panitumumab-IRDye800CW
Giri Krishnan, Nynke S. van den Berg, Naoki Nishio, Georgina Juniper, Jaqueline Pei, Quan Zhou, Guolan Lu, Y.-J. Lee, Kimberly Ramos, Andrei Iagaru, Fred M. Baik, A. Dimitrios Colevas, Brock A. Martin, Eben L. Rosenthal
Abstract
When intravenously infused, a tumour-targeted tracer localized to sentinel and metastatic lymph nodes. Further validation of an IV tumor-targeted tracer delivery approach for SLNB could dramatically change the practice of SLNB, allowing its application to other malignancies where the primary tumour is not accessible for local tracer injection.
Topics & Concepts
MedicineSentinel lymph nodeLymphSentinel nodeLymph nodePrimary tumorBiopsyRadiologyLymphadenectomyMetastasisNuclear medicinePathologyCancerBreast cancerInternal medicineHead and Neck Cancer StudiesCancer Diagnosis and TreatmentSalivary Gland Tumors Diagnosis and Treatment