Intranasally administered thermosensitive gel for brain-targeted delivery of rhynchophylline to treat Parkinson’s disease
Honglei Lin, Lukuan Xie, Lingrui Lv, Jianrong Chen, Feng Feng, Wenyuan Liu, Lingfei Han, Fulei Liu
Topics & Concepts
Nasal administrationPoloxamer 407PharmacologyPoloxamerBioavailabilityIn vivoNasal cavityBioadhesiveChemistryDrug deliveryMedicineSurgeryBiologyCopolymerBiotechnologyOrganic chemistryPolymerAdvanced Drug Delivery SystemsBotulinum Toxin and Related Neurological DisordersAlkaloids: synthesis and pharmacology