Characteristics and Prognosis of Tumor-Related Epilepsy During Tumor Evolution in Patients With <i>IDH</i> Wild-Type Glioblastoma
Johan Pallud, Alexandre Roux, Alessandro Moiraghi, Oumaima Aboubakr, Angela Rita Elia, Eléonore Guinard, Catherine Oppenheim, Arnault Tauziède‐Espariat, Eduardo Párraga, Martine Gavaret, Fabrice Chrétien, Gilles Huberfeld, Marc Zanello
Abstract
BACKGROUND AND OBJECTIVES: )-wild-type is almost unexplored longitudinally during the whole course of the disease. We assessed tumor-related epilepsy and seizure control during tumor evolution and the prognostic significance of tumor-related epilepsy. METHODS: test or Mann-Whitney rank-sum test for continuous variables. Predictors associated with tumor-related epilepsy and seizure control in unadjusted analysis were entered into backward stepwise logistic regression models. RESULTS: promoter methylation. DISCUSSION: -wild-type and the effects of surgery on seizure control argue for proper antiseizure medication and maximal safe resection. Tumor-related epilepsy is an independent predictor of a longer survival.