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Targeting the TLR4/NF-κB pathway in β-amyloid-stimulated microglial cells: A possible mechanism that oxysophoridine exerts anti-oxidative and anti-inflammatory effects in an in vitro model of Alzheimer’s disease

Rui Chen, Ziyu Wang, Zhongwen Zhi, Jisha Tian, Ying Zhao, Junshan Sun

2021Brain Research Bulletin23 citationsDOI

Topics & Concepts

Oxidative stressSuperoxide dismutaseTumor necrosis factor alphaTLR4Viability assayInflammationMicrogliaGlutathione peroxidaseChemistryPharmacologyNeuroinflammationBiologyEndocrinologyImmunologyBiochemistryIn vitroAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments
Targeting the TLR4/NF-κB pathway in β-amyloid-stimulated microglial cells: A possible mechanism that oxysophoridine exerts anti-oxidative and anti-inflammatory effects in an in vitro model of Alzheimer’s disease | Litcius