Inhibition of thrombin-activatable fibrinolysis inhibitor via DS-1040 to accelerate clot lysis in patients with acute pulmonary embolism: a randomized phase 1b study
Thomas Vanassche, Rachel Rosovsky, Farès Moustafa, Harry R. Büller, Annelise Segers, Indu Patel, Minggao Shi, Naoki Miyoshi, Venkatesh Mani, Zahi A. Fayad, Dominique Stéphan, Jeannot Schmidt, Michael Grosso, Victor F. Tapson, Peter Verhamme, Menno V. Huisman, Menno V. Huisman, Victor F. Tapson, Michael Grosso, Annelise Segers, Walter Ageno, Marianne Brodmann, David Jiménez, Guy Meyer, Saskia Middeldorp, Rachel Rosovsky, Sebastian Schellong, Peter Verhamme, Harry R. Büller, Patrick Bossuyt, Nick van Es, Peter Verhamme, Thomas Vanassche
Topics & Concepts
MedicinePlaceboClinical endpointPulmonary embolismFibrinolysisTolerabilityThrombusInternal medicineRandomized controlled trialMulticenter trialAnesthesiaCardiologyAdverse effectMulticenter studyPathologyAlternative medicineVenous Thromboembolism Diagnosis and ManagementBlood properties and coagulationAtrial Fibrillation Management and Outcomes