Design and synthesis of thiobarbituric acid analogues as potent urease inhibitors
Matee Ullah Khan, Misbah Aslam, Sohail Anjum Shahzad, Zulfiqar Ali Khan, Nazeer Ahmad Khan, Muhammad Ali, Sadia Naz, Jameel Rahman, Umar Farooq
Topics & Concepts
ChemistryThioureaUreaseStereochemistryActive siteBimetallic stripDocking (animal)EnzymeThiobarbituric acidMethyleneCombinatorial chemistryOrganic chemistryLipid peroxidationCatalysisMedicineNursingMicrobial Applications in Construction MaterialsEnzyme function and inhibitionBiochemical and Molecular Research