Unusual Ni⋯Ni interaction in Ni(<scp>ii</scp>) complexes as potential inhibitors for the development of new anti-SARS-CoV-2 Omicron drugs
Simranjeet Singh, Mukesh Choudhary
Abstract
(2) with a DNA duplex (PDB ID: 7D3T) and RNA (PDB ID: 7TDC) binding protein was also studied. Overall, this study suggests that Ni(ii) complexes can be considered as drug candidates against the Omicron variants of SARS-CoV-2.
Topics & Concepts
Schiff baseChemistryNickelLigand (biochemistry)StereochemistryBiochemistryReceptorOrganic chemistryMetal complexes synthesis and propertiesComputational Drug Discovery MethodsMetal-Organic Frameworks: Synthesis and Applications