A redox-enabled strategy for intramolecular hydroamination
Meredith A. Allen, Huy M. Ly, Geneviève F. O'Keefe, André M. Beauchemin
Abstract
-oxide. The steps are performed sequentially in a single pot, no catalyst is required, the conditions are mild, the process is highly functional group tolerant, and no chromatography is generally required for isolation. A robustness screen and a gram-scale example further support the practicality of this approach.
Topics & Concepts
HydroaminationIntramolecular forceRedoxChemistryCombinatorial chemistryNanotechnologyMaterials scienceStereochemistryOrganic chemistryRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques