Precision photothermal therapy and photoacoustic imaging by <i>in situ</i> activatable thermoplasmonics
Yahua Liu, Fengye Mo, Jialing Hu, Qunying Jiang, Xiuyuan Wang, Zhiqiao Zou, Xian‐Zheng Zhang, Dai‐Wen Pang, Xiaoqing Liu
Abstract
controllable plasmonic heating for thermoplasmonic activation. This enables monitoring of signal molecule dynamics, real-time photothermal and photoacoustic imaging of tumors and lymph node metastasis, and targeted photothermal therapy without unwanted phototoxicity to normal tissues. Our study provides a practical solution to the non-specificity problem in phototherapy and offers precision cancer therapeutic and theranostic strategies. This work may advance the development of ultrasensitive disease diagnosis and precision medicine.
Topics & Concepts
Photothermal therapyPhotoacoustic imaging in biomedicinePhototoxicityNanotechnologyMolecular imagingMedicineMaterials scienceChemistryIn vivoOpticsBiologyBiochemistryIn vitroPhysicsBiotechnologyNanoplatforms for cancer theranosticsPhotoacoustic and Ultrasonic ImagingPhotodynamic Therapy Research Studies