Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes
Ying Chen, Gregory B. Craven, Roarke A. Kamber, Adolfo Cuesta, Serhii Zhersh, Yurii S. Moroz, Michael C. Bassik, Jack Taunton
Topics & Concepts
ChemistryElectrophileProteomeChemical biologyCysteineCovalent bondSmall moleculeEnantiomerNucleophileCombinatorial chemistryStereochemistryBiochemistryEnzymeOrganic chemistryCatalysisClick Chemistry and ApplicationsPeptidase Inhibition and AnalysisChemical Synthesis and Analysis