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Synthesis, Spectroscopic Characterization, Single-Crystal Structure, Hirshfeld Surface Analysis, and Antimicrobial Studies of 3-Acetoxy-2-methylbenzoic Anhydride

Şükriye Çakmak, Sevgi Kansız, Mohammad Azam, Aysel Veyisoğlu, Hasan Yakan, Min Kim

2022ACS Omega12 citationsDOIOpen Access PDF

Abstract

. A Hirshfeld surface analysis was performed to record various intermolecular interactions, indicating the stabilization of the AMA structure by the intermolecular weak C-H···O hydrogen bonds and π···π interactions. The title compound was screened for antibacterial and antifungal activities using a serial dilution technique under aseptic conditions. The results indicate that the title compound has significant antibacterial properties but showed no antifungal behavior.

Topics & Concepts

Monoclinic crystal systemIntermolecular forceChemistryCrystal structureHydrogen bondProton NMRAcetic anhydrideCrystallographyElemental analysisSingle crystalStereochemistryOrganic chemistryMoleculeCatalysisPhenothiazines and Benzothiazines Synthesis and ActivitiesSynthesis and biological activityCrystal structures of chemical compounds
Synthesis, Spectroscopic Characterization, Single-Crystal Structure, Hirshfeld Surface Analysis, and Antimicrobial Studies of 3-Acetoxy-2-methylbenzoic Anhydride | Litcius