Iron catalyzed ketoalkylation and ketoalkylation/etherification of styrenes initiated by selective C–C bond cleavage
Meng-Ting Suo, Shuo Yang, Jun‐Cheng Yang, Zeyu Liu, Junjie Zhang, Li‐Na Guo
Abstract
A mild and efficient iron-catalyzed ketoalkyl-Heck-type coupling initiated by radical C–C bond cleavage is described. Furthermore, this concise catalytic system was also applicable for the three-component ketoalkylation/etherification of styrenes.
Topics & Concepts
ChemistryCatalysisCleavage (geology)Bond cleavagePolymer chemistryMedicinal chemistryOrganic chemistryGeotechnical engineeringFracture (geology)EngineeringCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsSulfur-Based Synthesis Techniques