NGF-Induced Nav1.7 Upregulation Contributes to Chronic Post-surgical Pain by Activating SGK1-Dependent Nedd4-2 Phosphorylation
Baowen Liu, Jin Zhang, Yishun Hong, Ningbo Li, Yi Liu, Mi Zhang, Wenyao Wu, Hua Zheng, Angelika Lampert, Xianwei Zhang
Topics & Concepts
Downregulation and upregulationNerve growth factorTropomyosin receptor kinase ADorsal root ganglionNociceptorMedicineNAV1Sodium channelSGK1Nerve injuryNeuroscienceInternal medicineNociceptionAnesthesiaChemistryBiologyReceptorAnatomyDorsumGlucocorticoidGeneSodiumBiochemistryOrganic chemistryPain Mechanisms and TreatmentsNeuropeptides and Animal PhysiologyNerve injury and regeneration