Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice
Masato Hoshi, Yosuke Osawa, Kentaro Nakamoto, Nanaka Morita, Yasuko Yamamoto, Tatsuya Ando, Chieko Tashita, Toshitaka Nabeshima, Kuniaki Saito
Topics & Concepts
KynurenineAryl hydrocarbon receptorIndoleamine 2,3-dioxygenaseCarbon tetrachlorideLiver injuryPharmacologyChemistryCCL4Knockout mouseTryptophanMedicineReceptorBiochemistryGeneTranscription factorOrganic chemistryAmino acidTryptophan and brain disordersStress Responses and CortisolBipolar Disorder and Treatment