Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids
Lan T.M. Dao, Zhen You, Lu Lu, Tianyang Xu, Avijite Kumer Sarkar, Hui Zhu, Miao Liu, Riccardo Calandrelli, George Yoshida, Pei Lin, Yifei Miao, Sarah Mierke, Srijan Kalva, Haining Zhu, Mingxia Gu, Sudhakar Vadivelu, Sheng Zhong, L. Frank Huang, Ziyuan Guo
Topics & Concepts
OrganoidBiologyTranscriptomeBlood–brain barrierInduced pluripotent stem cellHuman brainCrosstalkCentral nervous systemPhenotypeNeuroscienceCell biologyEmbryonic stem cellGeneGeneticsGene expressionOpticsPhysicsBarrier Structure and Function StudiesRenal and related cancersVascular Malformations Diagnosis and Treatment