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Prescription Fill Patterns for Commonly Used Drugs During the COVID-19 Pandemic in the United States

Muthiah Vaduganathan, Jeroen van Meijgaard, Mandeep R. Mehra, Jacob Joseph, Christopher J. O’Donnell, Haider J. Warraich

2020JAMA165 citationsDOIOpen Access PDF

Abstract

Conflicting information regarding the benefits of hydroxychloroquine/chloroquine and azithromycin in coronavirus disease 2019 (COVID-19) treatment and hypothetical concerns for drugs, such as angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), have challenged care during the pandemic. 1 However, limited data are available about how prescription of these therapies has changed. The objective of this exploratory analysis was to evaluate prescription patterns of these therapies, along with other commonly used drugs for reference, in the United States during the COVID-19 pandemic. We hypothesized that the prescription of hydroxychloroquine/chloroquine and azithromycin would exceed historical estimates while ACE inhibitor/ ARB use would be reduced.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)Pandemic2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Medical prescriptionBetacoronavirusMEDLINECoronavirus InfectionsMedical emergencyVirologyIntensive care medicinePharmacologyInternal medicineOutbreakInfectious disease (medical specialty)LawDiseasePolitical scienceCOVID-19 Clinical Research StudiesPharmaceutical Practices and Patient OutcomesPharmacovigilance and Adverse Drug Reactions
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