Notoginsenoside Fc, a novel renoprotective agent, ameliorates glomerular endothelial cells pyroptosis and mitochondrial dysfunction in diabetic nephropathy through regulating HMGCS2 pathway
Yilan Shen, Wei Chen, Kanghong Lin, Haiying Zhang, Xieyi Guo, Xiaoning An, Liu Yang, Niansong Wang, Youhua Xu, Dingkun Gui
Topics & Concepts
PyroptosisDiabetic nephropathyTXNIPMFN2Oxidative stressPharmacologyChemistrymitochondrial fusionKidneyMedicineBiologyInternal medicineEndocrinologyInflammasomeInflammationBiochemistryMitochondrial DNAThioredoxinGeneGinseng Biological Effects and ApplicationsInflammasome and immune disordersChronic Kidney Disease and Diabetes