Identification of inhibitors targeting polyketide synthase 13 of Mycobacterium tuberculosis as antituberculosis drug leads
Xiao Wang, Wenting Zhao, Bin Wang, Wei Ding, Hao Guo, Hongyi Zhao, Jianzhou Meng, Sihan Liu, Yu Lu, Yishuang Liu, Dongfeng Zhang
Topics & Concepts
ChemistryMycobacterium tuberculosisPolyketide synthasePolyketidePharmacophoreEnzymeSurface plasmon resonanceDrug discoveryMycolic acidIC50TuberculosisStereochemistryBiochemistryIn vitroBiosynthesisNanotechnologyMedicinePathologyNanoparticleMaterials scienceMicrobial Natural Products and BiosynthesisCancer therapeutics and mechanismsPlant Disease Resistance and Genetics