Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy
Mukesh Gangar, Sandeep Goyal, Digambar Raykar, Princy Khurana, Ashwita M. Martis, Avijit Goswami, Ishani Ghoshal, Ketul V. Patel, Yadav Kacharu Nagare, Santosh Shivanand Raikar, Apurba Mukherjee, Rajath Cyriac, Jean‐François Paquin, Aditya Kulkarni
Topics & Concepts
Stimulator of interferon genesCancer immunotherapyPhosphodiesteraseChemistryImmunotherapyInterferonIn vitroIn vivoBiochemistryCancer cellADMEEnzymePharmacologyCancerCancer researchImmune systemBiologyCytosolImmunologyBiotechnologyGeneticsinterferon and immune responsesProtein Tyrosine PhosphatasesCytokine Signaling Pathways and Interactions