Diagnostic Accuracy of MRI for the Detection of Malignant Peripheral Nerve Sheath Tumors: A Systematic Review and Meta-Analysis
Mitchell P. Wilson, Prayash Katlariwala, Gavin Low, M. Hassan Murad, Matthew D. F. McInnes, Line Jacques, Andrew Jack
Abstract
Combining features such as diffusion restriction optimizes the diagnostic accuracy of MRI for detecting MPNSTs. However, limitations in the literature, including variability and risk of bias, necessitate additional methodologically rigorous studies to allow subgroup analysis and further evaluate the combination of clinical and MRI features for MPNST diagnosis.
Topics & Concepts
MedicineMeta-analysisPeripheral nerveDiagnostic accuracyMalignant peripheral nerve sheath tumorPathologyFirst lineRadiologyAnatomyInternal medicineImmunohistochemistryNeurofibromatosis and Schwannoma CasesMeningioma and schwannoma managementBone Tumor Diagnosis and Treatments