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Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss

Dongxian Guan, Yuqin Men, Alexander Bartlett, Mario Andrés Salazar Hernández, Jie Xu, Xinchi Yi, Hu-song Li, Dong Kong, Ralph Mazitschek, Umut Özcan

2024Cell Metabolism20 citationsDOIOpen Access PDF

Topics & Concepts

LeptinHDAC6ObesityEndocrinologyInternal medicineLeptin receptorHistone deacetylaseMedicineBiologyHistoneGeneGeneticsHistone Deacetylase Inhibitors ResearchRegulation of Appetite and ObesityNeuropeptides and Animal Physiology
Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss | Litcius