Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases
E. Weeks, Jacob C. Ulirsch, Nathan Cheng, Brian L. Trippe, Rebecca S. Fine, Jenkai Miao, Tejal A. Patwardhan, Masahiro Kanai, Joseph Nasser, Charles P. Fulco, Katherine Tashman, François Aguet, Taibo Li, José Ordovás-Montañés, Christopher S. Smillie, Moshe Biton, Alex K. Shalek, Ashwin N. Ananthakrishnan, Ramnik J. Xavier, Aviv Regev, Rajat M. Gupta, Kasper Lage, Kristin Ardlie, Joel N. Hirschhorn, Eric S. Lander, J Engreitz, Hilary K. Finucane
Topics & Concepts
BiologyGenome-wide association studyQuantitative trait locusComputational biologyPolygeneGeneGeneticsTraitGenomeGenetic associationSingle-nucleotide polymorphismComputer scienceGenotypeProgramming languageGenetic Associations and EpidemiologyRNA modifications and cancerBioinformatics and Genomic Networks