Litcius/Paper detail

Unveiling the molecular and immunological drivers of antibody–drug conjugates in cancer treatment

Alfred Zippelius, Sara M. Tolaney, Paolo Tarantino, Joseph P. Balthasar, Greg M. Thurber

2025Nature reviews. Cancer34 citationsDOI

Topics & Concepts

Immune systemCancer treatmentComputational biologyImmunotherapyDrugCancer researchCancerDrug developmentMedicineRational designCytotoxic T cellBiologyClinical trialCancer therapyImmunologyCytotoxicityClinical efficacyConjugateCancer immunotherapyChimeric antigen receptorAntigenCellBioinformaticsClinical PracticeAntibody-drug conjugateCancer cellAcquired immune systemPrecision medicineCell cultureDendritic cellDrug discoveryHER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchCAR-T cell therapy research
Unveiling the molecular and immunological drivers of antibody–drug conjugates in cancer treatment | Litcius