Xist nucleates local protein gradients to propagate silencing across the X chromosome
Yolanda Markaki, Johnny Gan Chong, Yuying Wang, Elsie Jacobson, Christy Luong, Shawn Y.X. Tan, Joanna W. Jachowicz, Mackenzie Strehle, Davide Maestrini, Abhik K. Banerjee, Bhaven A. Mistry, Iris Dror, François Dossin, Johannes Schöneberg, Édith Heard, Mitchell Guttman, Tom Chou, Kathrin Plath
Topics & Concepts
XISTBiologyChromatinGene silencingRNACell biologyChromosome segregationGeneticsX-inactivationGeneChromosomeX chromosomeCancer-related molecular mechanisms researchRNA Research and SplicingRNA modifications and cancer