The GSA Family in 2025: A Broadened Sharing Platform for Multi-omics and Multimodal Data
Sisi Zhang, Xu Chen, Enhui Jin, Anke Wang, Tingting Chen, Xiaolong Zhang, Junwei Zhu, Lili Dong, Yanling Sun, Caixia Yu, Yubo Zhou, Zhuojing Fan, Huanxin Chen, Shuang Zhai, Yubin Sun, Qiancheng Chen, Jingfa Xiao, Shuhui Song, Zhang Zhang, Yīmíng Bào, Yanqing Wang, Wenming Zhao
Abstract
The Genome Sequence Archive family (GSA family) provides a comprehensive suite of database resources for archiving, retrieving, and sharing multi-omics data for the global academic and industrial communities. It currently comprises four distinct database members: the Genome Sequence Archive (GSA, https://ngdc.cncb.ac.cn/gsa), the Genome Sequence Archive for Human (GSA-Human, https://ngdc.cncb.ac.cn/gsa-human), the Open Archive for Miscellaneous Data (OMIX, https://ngdc.cncb.ac.cn/omix), and the Open Biomedical Imaging Archive (OBIA, https://ngdc.cncb.ac.cn/obia). Compared to its 2021 version, the GSA family has expanded significantly by introducing a new repository, the OBIA, and by comprehensively upgrading the existing databases. Notable enhancements to the existing members include broadening the range of accepted data types, strengthening quality control systems, improving the data retrieval system, and refining data-sharing management mechanisms.