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Design, synthesis, biological evaluation and molecular docking of new 1,3,4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents

Az‐eddine El Mansouri, Ali Oubella, Ahmad Mehdi, Moulay Youssef AitItto, Mohamed Zahouily, Hamid Morjani, Hassan B. Lazrek

2020Bioorganic Chemistry38 citationsDOI

Topics & Concepts

ChemistryDocking (animal)OxadiazoleStereochemistryApoptosisCell cycleAnnexinCell cycle checkpointCytotoxicityCell cultureIn vitroHydrogen bondBiochemistryOrganic chemistryMoleculeNursingGeneticsBiologyMedicineSynthesis and biological activityCancer therapeutics and mechanismsClick Chemistry and Applications
Design, synthesis, biological evaluation and molecular docking of new 1,3,4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents | Litcius