Osthole inhibits malignant phenotypes and induces ferroptosis in KRAS-mutant colorectal cancer cells via suppressing AMPK/Akt signaling
Xinghua Zhou, Jian Kang, Liangliang Zhang, Cheng Yue
Topics & Concepts
PI3K/AKT/mTOR pathwayKRASProtein kinase BCancer researchAutophagyAMPKSignal transductionChemistryApoptosisBiologyCell biologyPhosphorylationColorectal cancerCancerProtein kinase ABiochemistryGeneticsFerroptosis and cancer prognosisCancer-related molecular mechanisms researchRetinoids in leukemia and cellular processes