Oncogenic mutations on Rac1 affect global intrinsic dynamics underlying GTP and PAK1 binding
Saliha Ece Acuner, Fidan Sumbul, Hamdi Torun, Türkan Haliloǧlu
Topics & Concepts
RAC1PAK1MutantBiophysicsSerineCooperativityGTP'Cell biologyBiologyPhosphorylationChemistrySignal transductionBiochemistryGeneEnzymeForce Microscopy Techniques and ApplicationsCellular Mechanics and InteractionsProtein Structure and Dynamics