Sperm Transcriptome Analysis Accurately Reveals Male Fertility Potential in Livestock
Rhesti Indriastuti, Berlin Pandapotan Pardede, Asep Gunawan, Mokhamad Fakhrul Ulum, Raden Iis Arifiantini, Bambang Purwantara
Abstract
Nowadays, selection of superior male candidates in livestock as a source of frozen semen based on sperm quality at the cellular level is not considered accurate enough for predicting the potential of male fertility. Sperm transcriptome analysis approaches, such as messenger RNA levels, have been shown to correlate with fertility rates. Using this technology in livestock growth has become the principal method, which can be widely applied to predict male fertility potential in the livestock industry through the analysis of the sperm transcriptome. It provides the gene expression to validate the function of sperm in spermatogenesis, fertilization, and embryo development, as the parameters of male fertility. This review proposes a transcriptomic analysis approach as a high-throughput method to predict the fertility potential of livestock more accurately in the future.