TYMS Knockdown Suppresses Cells Proliferation, Promotes Ferroptosis via Inhibits PI3K/Akt/mTOR Signaling Pathway Activation in Triple Negative Breast Cancer
Lin Wang, Zheyi Wu, Yanyan Wang, Chunchun Chen, Yulong Li, Huiming Dong, Tingjing Yao, Gongsheng Jin, Zhenjie Wang
Topics & Concepts
PI3K/AKT/mTOR pathwayTriple-negative breast cancerGene knockdownCancer researchProtein kinase BSignal transductionCell growthChemistryBreast cancerCell biologyCancerBiologyApoptosisMedicineInternal medicineBiochemistryFerroptosis and cancer prognosisCancer, Lipids, and MetabolismCancer-related gene regulation