Litcius/Paper detail

Quantification of true lumen helical morphology and chirality in type B aortic dissections

Johan Bondesson, Ga‐Young Suh, Torbjörn Lundh, Michael D. Dake, Jason T. Lee, Christopher P. Cheng

2020American Journal of Physiology-Heart and Circulatory Physiology11 citationsDOI

Abstract

A novel definition of helical propagation of type B aortic dissections reveals a distinct bimodality, with the true lumen being either achiral (nonhelical) or exclusively right-handed. This right-handed chirality is consistent with anatomic and physiological phenomena such as right-handed twist during left ventricle contraction, helical blood flow, and tissue fiber direction. The helical character of aortic dissections may be useful for pathology research, diagnostics, treatment selection, therapeutic durability prediction, and aortic device design.

Topics & Concepts

AnatomyVentricleTwistAortic dissectionContraction (grammar)Helical computed tomographyBlood flowMedicineAortaCardiologyInternal medicineRadiologyComputed tomographyGeometryMathematicsAortic Disease and Treatment ApproachesCardiac Valve Diseases and TreatmentsElasticity and Material Modeling