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Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection

Kilian Schober, Florian Voit, Simon Grassmann, Thomas Müller, Joel Eggert, Sebastian Jarosch, Bianca Weißbrich, Patrick Hoffmann, Lisa Borkner, Enzo Nio, Lorenzo F. Fanchi, Christopher R. Clouser, Aditya Radhakrishnan, Lorenz Mihatsch, Philipp Lückemeier, Justin Leube, Georg Dössinger, Ludger Klein, Michael Neuenhahn, Jennifer D. Oduro, Luka Čičin‐Šain, Veit R. Buchholz, Dirk H. Busch

2020Nature Immunology119 citationsDOI

Topics & Concepts

ImmunodominanceT-cell receptorBiologyT cellRepertoireAntigenImmunologyAffinity maturationImmune systemVirologyPhysicsAcousticsT-cell and B-cell ImmunologyCytomegalovirus and herpesvirus researchImmune Cell Function and Interaction
Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection | Litcius