Discovery of tetrahydroisoquinolineindole derivatives as first dual PRMT5 inhibitors/hnRNP E1 upregulators: Design, synthesis and biological evaluation

Wenhui Chu, Na Yang, Jinhe Zhang, Jinhe Zhang, Yue Li, Jiali Song, Zhipeng Deng, Ning Meng, Juan Zhang, Juan Zhang, Kongkai Zhu, Cheng‐Shi Jiang