Litcius/Paper detail

Designing of biosafe, multifunctional alginate-nanoclay hydrogels for environmental applications: structure, swelling properties, and cadmium sorption

N.V. Guzenko, Olena Goncharuk, Yu. M. Samchenko, Konrad Terpiłowski, Katarzyna Grygorczuk-Płaneta, S. М. Dybkova, Bartosz Kondracki, Katarzyna Szewczuk‐Karpisz

2025International Journal of Biological Macromolecules11 citationsDOIOpen Access PDF

Abstract

Composite hydrogels (HGs) based on sodium alginate (Alg), with nanoclay montmorillonite (MMT) and LaponiteRD (Lap) fillers, were synthesized using ionic cross-linking with calcium ions (Ca 2+ ). The HGs structure was investigated by SEM-EDX, XRD, and FTIR, whereas сation exchange capacity (CEC) and variable surface charge were determined using potentiometric titration. The influence of filler content, cross-linking agent concentration, and pH on the swelling and sorption capacity towards cadmium ions (Cd 2+ ) of HGs was analyzed in detail. The cross-linking agent concentration influenced the swelling mechanism of the alginate-based composites with clays as well as their specific type of water diffusion based on the Fick equation. The CaCl 2 concentration ( C CaCl2 ) of 0.3–0.5 wt% was found as optimal for synthesizing mechanically stable HGs with a large swelling degree and sorption ability for Cd 2+ ions. The sorption capacities calculated based on the Langmuir model were 1.36, 1.19, and 1.33 mmol/g for Alg, Alg/20%MMT, and Alg/20%Lap synthesized using 0.3 wt% CaCl 2 , respectively. The in vitro tests on genotoxicity and cytotoxicity of HGs, performed using the mouse fibroblast cell culture L-929, proved the biosafety of the developed composites for the environment. • Alginate-based hydrogels (HGs) were filled with two types of nanoclays. • Cross-linker concentration of 0.25 wt% provided maximum swelling for all systems. • HGs showed a great sorption activity and affinity for cadmium (Cd) ions. • The greatest efficiency of Cd removal was noted for HG with laponite (even 97.8 %). • All tested HGs were biosafe in terms of cytotoxicity and genotoxicity assays.

Topics & Concepts

SwellingSorptionSelf-healing hydrogelsMontmorilloniteChemical engineeringNuclear chemistrySwelling capacityMaterials scienceChemistryCalcium alginatePotentiometric titrationAdsorptionPolymer chemistryComposite materialCalciumIonOrganic chemistryEngineeringHydrogels: synthesis, properties, applications3D Printing in Biomedical ResearchTherapeutic Uses of Natural Elements