Resveratrol mediates the miR-149/HMGB1 axis and regulates the ferroptosis pathway to protect myocardium in endotoxemia mice
Xiaoli Wang, Alimujiang Simayi, Juan Fu, Xuan Zhao, Guiping Xu
Abstract
Sepsis is an unusual systemic reaction. Resveratrol is involved in sepsis treatment. This study explored the mechanism of resveratrol in sepsis by regulating the miR-149/HMGB1 axis.
Topics & Concepts
ResveratrolHMGB1Cell biologyChemistryApoptosisPharmacologyCancer researchMedicineBiologyImmunologyInflammationBiochemistryMicroRNA in disease regulationFerroptosis and cancer prognosisRNA modifications and cancer