Litcius/Paper detail

Single-cell atlas of human liver and blood immune cells across fatty liver disease stages reveals distinct signatures linked to liver dysfunction and fibrogenesis

Owen P. Martin, Michael S. Wallace, Christopher Oetheimer, Hailey Patel, Michael Dillon Butler, Lai Ping Wong, Pinzhu Huang, Joshua Elbaz, Charlotte Costentin, Shadi Salloum, Zoe Reinus, Adaeze Obinelo, U Kim, Stuti G. Shroff, Kathleen E. Corey, Yury Popov, Edgar D. Charles, Ruslan I. Sadreyev, Raymond T. Chung, Nadia Alatrakchi

2025Nature Immunology17 citationsDOIOpen Access PDF

Topics & Concepts

Immune systemFatty liverBiologyImmune DysfunctionCellHepatic stellate cellDiseaseLiver diseasePathologyImmunologyMedicineGeneticsBiochemistrySingle-cell and spatial transcriptomicsDiabetes and associated disordersLiver Disease Diagnosis and Treatment