Natural carbazole alkaloid murrayafoline A displays potent anti-neuroinflammatory effect by directly targeting transcription factor Sp1 in LPS-induced microglial cells
Chaohua Li, Ying Zhou, Pengfei Tu, Ke‐Wu Zeng, Yong Jiang
Topics & Concepts
NeuroinflammationChemistryMicrogliaGene knockdownPharmacologyMAPK/ERK pathwayCell biologySignal transductionBiochemistryInflammationBiologyImmunologyApoptosisNeuroinflammation and Neurodegeneration MechanismsGenomics, phytochemicals, and oxidative stressChemokine receptors and signaling