Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M. Billingsley, Xisha Huang, Rakan El‐Mayta, Jingya Qin, Neil C. Sheppard, Carl H. June, Michael J. Mitchell
Topics & Concepts
ToxicityCancer researchT cellCytokineCytokine release syndromeEpidermal growth factor receptorReceptorImmune systemBiologyChemistryMedicineImmunologyInternal medicineBiochemistryChimeric antigen receptorCAR-T cell therapy researchMonoclonal and Polyclonal Antibodies ResearchNanofabrication and Lithography Techniques