Inhibition of USP14 enhances anti-tumor effect in vemurafenib-resistant melanoma by regulation of Skp2
Ting Wu, Chengyun Li, Changlong Zhou, Xiaxia Niu, Gege Li, Yali Zhou, Xinsheng Gu, Hongmei Cui
Topics & Concepts
VemurafenibCancer researchMelanomaDeubiquitinating enzymeMAPK/ERK pathwayBiologyChemistryUbiquitinMolecular biologySignal transductionBiochemistryMetastatic melanomaGeneMelanoma and MAPK PathwaysNF-κB Signaling PathwaysCutaneous Melanoma Detection and Management