Hydroxycamptothecin (HCPT)-loaded PEGlated lipid–polymer hybrid nanoparticles for effective delivery of HCPT: QbD-based development and evaluation
Ziwei Ma, Jingjing Liu, Xiaowen Li, Ying Xu, Dongchun Liu, Haibing He, Yanjiao Wang, Xing Tang
Topics & Concepts
Polyethylene glycolChemistryIn vivoCytotoxicityPharmacologyPLGADrug deliveryIC50NanoparticleIn vitroMaterials scienceNanotechnologyBiochemistryOrganic chemistryMedicineBiologyBiotechnologyNanoparticle-Based Drug DeliveryNeutropenia and Cancer InfectionsCancer therapeutics and mechanisms