Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients
Hai-qiong Yu, Bao-qing Sun, Zhang-fu Fang, Jin-cun Zhao, Xiaoyu Liu, Yimin Li, Xi-zhuo Sun, Hong-feng Liang, Bei Zhong, Zhi-feng Huang, Pei-yan Zheng, Li-feng Tian, Hui‐Qi Qu, De-chen Liu, Er-yi Wang, Xiao-jun Xiao, Shi-yue Li, Feng Ye, Li Guan, Dong-sheng Hu, Håkon Håkonarson, Zhi-Gang Liu, Nanshan Zhong
Abstract
<b>Humoral immune response to SARS-CoV-2 showed an early response of IgA, instead of IgM, in COVID-19 patients. As highlighted by this study, enhanced IgA responses observed in severe COVID-19 might confer damaging effects in severe COVID-19.</b>https://bit.ly/3fA7c1I
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakImmune systemImmunologyAntibody responseVirologyImmunoglobulin ASars virusBiologyMedicineImmunoglobulin GPathologyOutbreakDiseaseInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesImmune responses and vaccinations