Reviewing the complexities of bacterial biocide susceptibility and in vitro biocide adaptation methodologies
Peter O’Reilly, Genevieve Loiselle, Ryan Darragh, Carmine J. Slipski, Denice C. Bay
Abstract
Decreased bacterial susceptibility to biocides raises concerns due to their influences on antibiotic resistance. The lack of standardized breakpoints, established methods, and consistent terminology complicates this research. This review summarizes techniques for studying biocide resistance mechanisms, susceptibility testing, and in-vitro adaptation methods, highlighting their benefits and limitations. Here, the challenges in studying biocide susceptibility and the need for standardized approaches in biocide research are emphasized for commonly studied biocide classes.
Topics & Concepts
BiocideMicrobiologyAdaptation (eye)BiologyChemistryOrganic chemistryNeuroscienceAntimicrobial agents and applicationsBacterial biofilms and quorum sensingBacillus and Francisella bacterial research