Binding-induced activation of CRISPR-Cas12a using PAM-engineered toehold switch and DNA tile architectures for enhanced detection of thrombin
Kai Zhang, Yuwen Bao, Changjin Ou, Guoyin Zhu, Yizhou Zhang
Topics & Concepts
CRISPRTileDNAChemistryNanotechnologyBiophysicsCell biologyMaterials scienceBiologyGeneBiochemistryComposite materialAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringBiosensors and Analytical Detection