Saikosaponin D exacerbates acetaminophen-induced liver injury by sabotaging GABARAP-SNARE complex assembly in protective autophagy
Guifang Fan, Xiaojiaoyang Li, Fanghong Li, Ranyun Chen, Xiaoyong Xue, Le Wang, Qi Zheng, Shuni Duan, Ranyi Luo, Rong Sun, Runping Liu
Topics & Concepts
AutophagyPharmacologyAcetaminophenChemistryULK1MedicineBiochemistryEnzymeAMPKProtein kinase AApoptosisAutophagy in Disease and TherapyDrug-Induced Hepatotoxicity and ProtectionBerberine and alkaloids research