Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy
Young Mi Oh, Seong Won Lee, Woo Kyung Kim, Shawei Chen, Victoria A. Church, K. Lynn Cates, Tiandao Li, Bo Zhang, Roland E. Dolle, Sonika Dahiya, Stephen C. Pak, Gary A. Silverman, David H. Perlmutter, Andrew S. Yoo
Topics & Concepts
NeuroscienceAutophagyHuntington's diseaseDiseaseNeurodegenerationPsychologyStriatumBiologyMedicineDopamineInternal medicineGeneticsApoptosisGenetic Neurodegenerative DiseasesMitochondrial Function and PathologyNeurological disorders and treatments