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Development of Diverse Range of Biologically Relevant Carbohydrate‐Containing Molecules: Twenty Years of Our Journey**

Vinod K. Tiwari

2021The Chemical Record44 citationsDOI

Abstract

There is an increasing demand for significant amount of carbohydrate-containing molecules owing to their complete chemical, biological, and pharmacological investigations to better understand their role in many important biological events. Clinical studies of a wide range of simple carbohydrates or their derivatives, glycohybrids, glycoconjugates, and neoglycoconjugates have been conducted worldwide for the successful treatment of various frontline diseases. Herein, a brief perspective of carbohydrate-based molecular scaffolding and my experience during the last 20 years in the area of synthetic carbohydrate chemistry, mainly for their impact in drug discovery & development, is presented.

Topics & Concepts

GlycoconjugateCarbohydrateDrug discoveryBiological activityChemistryBiochemistryCombinatorial chemistryComputational biologyBiologyIn vitroCarbohydrate Chemistry and SynthesisGlycosylation and Glycoproteins ResearchClick Chemistry and Applications
Development of Diverse Range of Biologically Relevant Carbohydrate‐Containing Molecules: Twenty Years of Our Journey** | Litcius