RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons

James D. Thomas, Jacob T. Polaski, Qing Feng, Emma J. De Neef, Emma R. Hoppe, Maria McSharry, Joseph Pangallo, Austin M. Gabel, Andrea E. Belleville, Jacqueline Watson, Naomi T. Nkinsi, Alice H. Berger, Robert K. Bradley