Discovery of 1,2,4-triazine dithiocarbamate derivatives as NEDDylation agonists to inhibit gastric cancers
Jian Song, Yuan Liu, Xinying Yuan, Wenbo Liu, Yin-Ru Li, Guang-Xi Yu, Xin-Yi Tian, Yanbing Zhang, Xiang-Jing Fu, Sai‐Yang Zhang
Topics & Concepts
NeddylationChemistryCell cycleApoptosisCancer cellCell growthCellCancerCancer researchCell biologyBiochemistryPharmacologyBiologyUbiquitinGeneGeneticsUbiquitin ligaseUbiquitin and proteasome pathwaysCancer-related gene regulationPeptidase Inhibition and Analysis