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Design, synthesis, and in silico insights of novel N’-(2-oxoindolin-3-ylidene)piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors

Wagdy M. Eldehna, Youmna A Habib, Abeer E. Mahmoud, Mohamed F. Barghash, Zainab M. Elsayed, Ahmed E. Elsawi, Raed M. Maklad, Mahmoud Rashed, Amira Khalil, Sherif Hammad, Mamdouh M. Ali, Ahmed M. El Kerdawy

2024Bioorganic Chemistry16 citationsDOI

Topics & Concepts

CarbohydrazideChemistryPiperidineIn silicoCombinatorial chemistryPharmacologyStereochemistryMedicinal chemistryBiochemistryGeneMedicineAngiogenesis and VEGF in CancerSynthesis and biological activityCytokine Signaling Pathways and Interactions
Design, synthesis, and in silico insights of novel N’-(2-oxoindolin-3-ylidene)piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors | Litcius